In light of this unmet medical need, the development of chimeric antigen receptor (CAR) T-cell therapy has emerged as a promising approach for the treatment of relapsed, refractory MM (RRMM).ĬAR T-cell therapy involves the genetic modification of cellular therapies, which have shown significant efficacy in achieving deep and durable remissions in other B-cell malignancies.Įarly studies of CAR T-cell therapy in RRMM have demonstrated remarkable response rates, however, long-term durability remains an area of ongoing research. Multiple myeloma (MM) is a hematologic malignancy characterized by the clonal proliferation of transformed plasma cells.ĭespite significant progress in MM treatment, a cure remains elusive for the majority of patients, especially those with triple-class refractory MM who have developed resistance to immunomodulatory agents, proteasome inhibitors, and monoclonal antibodies. Shane Swatts Miguel López de Silanes Gómez Carmelo Chines Fabrizio Chines Benoit COLLET Nick Atkins Rachna Murthy Jonathan Roos Alessandro Moroni Yvonne Hernández González Rick Good Samer Hamada Dr. FAAO Christopher Starr Benjamin Sullivan John Gelles Yang Liu Sabrina Zappia Dr. #TFOSLifestyle #eyesarethestory #ocularsurfacedisease #dryeye #eyecare #cosmetics #scienceofeyes #teamwork #optocosmetics Bridgitte Shen Lee, OD, FAAO, FBCLA, FEAOO, Dipl ABO Leslie O'Dell, O.D. Look forward to sharing more of “The Story” around the world! Key takeaway: Education is paramount (and too many female ophthalmologists & patients in the Middle East apply eyeliner to their waterline!) Lazreg Sihem from Algeria and discussed how we can better educate clinicians and patients worldwide on eye-safe cosmetics. And, very proud of Dad who gave the Keynote and received an award and recognition for his global achievements. Great honor to be on stage with my father, David Sullivan, and Stefano Barabino from Milano. “I felt after that day and everything following it, we were able to really come together and finish really strong,” Sullivan said.Whirlwind visit to Abu Dhabi to present at the 20th Emirates Society of Ophthalmology Conference - about how cosmetics impact the ocular surface. Sullivan said losing Jent was an unexpected tragedy. I struggled with that, and I had a great race in the 100 free, which was awesome. I don’t feel I had it (in prelims and finals). “Every time I went in the water, I felt amazing. Sullivan, who will swim for the University of Florida, got the Greyhounds’ other victory, winning the 100 freestyle in 44.09 seconds. Enoch finished in second in the 200 individual medley and the 500 freestyle. Plumb said Enoch came a long way this season. Shackell was joined on the 400 freestyle relay by his brother, sophomore Andrew Shackell, and junior Gregg Enoch and senior A.J. “Aaron had a tremendous meet,” Plumb said. Shackell also was on the winning 200 medley relay with senior Sean Sullivan, junior Brandon Malicki and sophomore Michael Gorley. Shackell had set a national record in the 200 freestyle in the preliminaries with a time of 1:32.85, breaking Carson Foster’s 2019 national mark of 1:32.99. Senior Aaron Shackell, who is headed to the University of California in Berkeley, captured the 200-yard freestyle in 1 minute, 33.68 seconds ,and won the 500 freestyle in 4:15.35. I think the guys really had to step up (in the state finals). Any time you walk out of this meet with several Ws, you feel like it was a good meet. The top-end performances were outstanding. “To win takes talent, to repeat takes character, so we’ll take it,” Plumb said., “This team really came to swim these past two days. Carmel won with 363 points, more than 100 points ahead of second place Zionsville with 257. 25 in the IHSAA state boys swimming and diving state finals at the IU Natatorium at IUPUI. The Greyhounds captured their ninth consecutive title Feb. “It was a really challenging season with the passing of Michael,” Greyhounds coach Chris Plumb said. The previous month, junior Michael Jent died from injures suffered in an automobile accident, which happened heading to swimming practice. The state finals showing for the Carmel High School boys swimming team was an emotional one. Shackell set the record with a time of 1:32.85. Correction: In the original version of this story, the national record time in the 200 freestyle set by Aaron Shackell was incorrect.
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